Mitomycin Injection 40mg – Product Description
Mitomycin is an antineoplastic agent derived from the bacterium Streptomyces caespitosus. It is primarily used in the treatment of various types of cancer, including bladder cancer, gastric cancer, and pancreatic cancer. Mitomycin works by inhibiting DNA synthesis, which ultimately leads to cell death. This medication is typically administered via injection and is often used in combination with other chemotherapy agents to enhance its effectiveness.
Uses of Mitomycin Injection
- Bladder Cancer: Used as a treatment option for superficial bladder cancer.
- Gastric Cancer: Administered in cases of advanced gastric cancer.
- Pancreatic Cancer: Utilized in combination with other chemotherapeutic agents for treating pancreatic cancer.
- Other Cancers: May be used off-label for various other malignancies as determined by a healthcare provider.
Technical Data
| Parameter | Details |
|---|---|
| Active Ingredient | Mitomycin |
| Strength | 40 mg |
| Formulation | Injectable solution |
| Route of Administration | Intravenous (IV) or intravesical |
| Indications | Bladder cancer, gastric cancer, pancreatic cancer, and other malignancies |
| Mechanism of Action | Alkylating agent that inhibits DNA synthesis |
| Storage Conditions | Store at room temperature (20-25°C) |
| Shelf Life | Typically 24 months from the date of manufacture |
| Side Effects | Nausea, vomiting, myelosuppression, renal toxicity, and potential for secondary malignancies |
| Contraindications | Known hypersensitivity to mitomycin, pregnancy, and breastfeeding |
| Drug Interactions | May interact with other chemotherapeutic agents and medications that affect bone marrow function |
Key Points
- Administration: Mitomycin is administered under the supervision of a healthcare professional, typically in a clinical setting.
- Monitoring: Patients receiving Mitomycin should be closely monitored for side effects, particularly myelosuppression, which can lead to increased risk of infection and bleeding.
- Patient Education: Patients should be informed about potential side effects and the importance of adhering to follow-up appointments for monitoring blood counts and overall health.
Mitomycin Injection 40mg is a potent chemotherapeutic agent that plays a crucial role in the management of certain cancers, and its use should be carefully considered and monitored by healthcare professionals.