Mitomycin Injection Product Description
Mitomycin is an antineoplastic agent derived from the bacterium Streptomyces caespitosus. It is primarily used in the treatment of various types of cancer, including bladder cancer, gastric cancer, and pancreatic cancer. Mitomycin works by inhibiting DNA synthesis, leading to cell death, particularly in rapidly dividing cancer cells. The injection form of Mitomycin is typically administered intravenously and is often used in combination with other chemotherapy agents to enhance therapeutic efficacy.
Uses of Mitomycin Injection
- Bladder Cancer: Used as a treatment option for superficial bladder cancer, often administered intravesically.
- Gastric Cancer: Utilized in combination with other chemotherapeutic agents for advanced gastric cancer.
- Pancreatic Cancer: Sometimes included in treatment regimens for pancreatic adenocarcinoma.
- Other Cancers: May be used off-label for various other malignancies as determined by oncologists.
Technical Data
| Parameter | Details |
|---|---|
| Generic Name | Mitomycin C |
| Brand Name | Mutamycin, others |
| Formulation | Injection (IV) |
| Strength | 5 mg/10 mg/20 mg per vial |
| Indications | Bladder cancer, gastric cancer, pancreatic cancer, and others |
| Mechanism of Action | Alkylating agent that inhibits DNA synthesis |
| Administration Route | Intravenous (IV) or intravesical |
| Storage Conditions | Store at room temperature, protect from light |
| Side Effects | Nausea, vomiting, myelosuppression, renal toxicity, pulmonary toxicity |
| Contraindications | Hypersensitivity to Mitomycin, pregnancy, breastfeeding |
| Drug Interactions | May interact with other chemotherapeutic agents and anticoagulants |
Key Points
- Mitomycin is a potent chemotherapeutic agent with a specific focus on certain types of cancer.
- It is crucial to monitor patients for side effects, particularly myelosuppression and renal function.
- The administration of Mitomycin should be done under the supervision of a qualified healthcare professional, ensuring proper dosing and management of potential adverse effects.
Mitomycin injection remains a vital component in the oncological treatment landscape, providing options for patients with challenging malignancies.